張素瓊 名譽教授

學歷

經歷

榮譽與獎勵

論文著作

近五年代表著作

1. 1. Shui-Yuan Feng , Shu-Jing Wu , Yun-Ching Chang , Lean-Teik Ng and Sue-Joan Chang* .Stimulation of GLUT4 Glucose Uptake by Anthocyanin-Rich Extract from Black Rice (Oryza sativa L.) via PI3K/Akt and AMPK/p38 MAPK Signaling in C2C12 Cells.Metabolites.2022, 12(9),856; doi:10.3390/metabo12090856.
   2. Li-Ning Peng^*, Ming-Hsien Lin , Huei-Fang Lee, Chia-Chia Hsu, Sue-Joan Chang, Liang-Kung Chen. Clinical efficacy of Oligonol ® supplementation on metabolism and muscle health in middle-aged and older adults: A double-blinded randomized controlled trial. Arch Gerontol Geriatr. 2022. Jul 31; 103:104784.doi: 10.1016/j.archger.2022.104784 (SCI, IF= 4.163)
   3. Sue-Joan Chang *, Yin-Ching Chan, Hung-Wen Liu, Yun-Chin Chang and Shu-Jing Wu. Diet and health: functions and molecular mechanism. Proceeding of Canada –Taiwan bilateral conference on nutrition, health benefit and innovative processing of whole grains and pulses. 2022. P.20-32.
   4. Yun-Ching Chang, Yin-Chin Chan, Shu-Hui Hu, Ming-Yi Liu, Sue-Joan Chang*. The green tea polyphenol epigallocatechin-3-gallate attenuates age-associated muscle loss via regulation of myostatin and miR-486.Arch of Biochem and Biophy.2020 doi: https://doi.org/10.1016/j.abb.2020.108511. (SCI) ( IF: 4.013)
   5. Hung-Wen Liu, Yun-Ching Chang, Yin-Ching Chan, Shu-Hui Hu, Ming-Yi Liu, Sue-Joan Chang*. Dysregulations of mitochondrial quality control and autophagic flux at an early age lead to progression of sarcopenia in SAMP8 mice. Biogerontology. 2020 21(3):367-380. DOI:10.1007/s10522-020-09867-x (SCI) ( IF: 4.277)

   6. Yin-Ching Chan, Ci-Sian Wu, Tsai-Chen Wu, Yu-Hsuan Lin and Sue-Joan Chang *. A Standardized Extract of Asparagus officinalis Stem (ETAS^®) Ameliorates Cognitive Impairment, Inhibits Amyloid β Deposition via BACE-1 and Normalizes Circadian Rhythm Signaling via MT1 and MT2. Nutrients. 2019 Jul 17;11(7). pii: E1631. doi: 10.3390/nu11071631.

   7. Chang YC, Chen YT, Liu HW, Chen YA, Chen YJ and Chang SJ*.Oligonol Alleviates Sarcopenia by Regulation of Signaling Pathways Involved in Protein Turnover and Mitochondrial Quality.Mol Nutr Food Res.2019 Feb. doi: 10.1002/mnfr.201801102.

   8. Chang YC, Liu HW, Chen YT, Chen YA, Chen YJ and Chang SJ*. Resveratrol protects muscle cells against palmitate-induced cellular senescence and insulin resistance through ameliorating autophagic flux. J Food Drug Anal. 2018 Jul;26(3):1066-1074.
   9. Liu HW and Chang SJ. Moderate Exercise Suppresses NF-κB Signaling and Activates the SIRT1-AMPK-PGC1α Axis to Attenuate Muscle Loss in Diabetic db/db Mice. Front Physiol. 2018 May 29;9:636.
   10. Liu HW, Chen YJ, Chang YC and Chang SJ*. Oligonol, a Low-Molecular Weight Polyphenol Derived from Lychee, Alleviates Muscle Loss in Diabetes by Suppressing Atrogin-1 and MuRF1. Nutrients. 2017 Sep 20;9(9). pii: E1040.
   11. Liu HW, Chan YC, Wei CC, Chen YA, Wang MF and Chang SJ*. An alternative model for studying age-associated metabolic complications: Senescence-accelerated mouse prone 8. Exp Gerontol. 2017 Aug 23. 99:61-68.
   12. Hu SH, Chen KS, Liu MY, Cheung CK, Wang JC and Chang SJ*. Optimization of Submerged Cultivation Conditions for Production of Big Cup Culinary-Medicinal Mushroom Clitocybe maxima (Agaricomycetes) Biomass with Significant Antioxidative and Antihyperlipidemic activities. Int J Med Mushrooms. 2017;19(7):641-651.
   13. Chen YF, Shiau AL, Chang SJ, Fan NS, Wang CT, Wu CL and Jan JS. One-dimensional poly(L-lysine)-block-poly(L-threonine) assemblies exhibit potent anticancer activity by enhancing membranolysis. Acta Biomater. 2017 Jun;55:283-295.
   14. Liu HW, Wei CC, Chen YJ, Chen YA and Chang SJ*. Flavanol-rich lychee fruit extract alleviates diet-induced insulin resistance via suppressing mTOR/SREBP-1 mediated lipogenesis in liver and restoring insulin signaling in skeletal muscle. Mol Nutr Food Res. 2016,60:2288-2296.
   15. Liu HW, Wei CC and Chang SJ*. Low-molecular-weight Polyphenols Protect Kidney Damage through Suppressing NF-B and Modulating Mitochondrial Biogenesis in Diabetic db/db Mice. Food & Function. 2016; 7. 1941-9.
   16. Liu HW, Chan YC, Wang MF, Wei CC and Chang SJ*. Dietary (-)-epigallocatechin-3-gallate supplementation counteracts aging-associated skeletal muscle insulin resistance and fatty liver in senescence-accelerated mouse. J Agric Food Chem. 2015 Sep 30;63(38):8407-17.
   17. Liu HW, Huang WC, Yu WJ and Chang SJ*. Toona Sinensis ameliorates insulin resistance via AMPK and PPARγ pathways. Food Funct. 2015 Jun;6(6):1855-64.
   18. Liu HW, Tsai YT and Chang SJ*. Toona sinensis leaf extract inhibits lipid accumulation through up-regulation of genes involved in lipolysis and fatty acid oxidation in adipocytes. J Agric Food Chem. 2014 Jun 25;62(25):5887-96.

近三年國際會議

1. Oligonol alleviates sarcopenia: mechanisms of mitochondrial dynamic and autophagic flux. International Congress on Nutrition and Integrative Medicine (ICNIM 2018), Sapporo, Japan (Invited speaker)
2. Development of functional foods for glucose/lipid regulation. 2018 International Symposium on Functional Foods and Nutritional Supplements, Taipei, Taiwan (Invited speaker)
3. Polyphenol approaches to prevent / ameliorate sarcopenia. 2018 International Conference on Functional Food for improving Sarcopenia, Cachexia and Frailty, Taipei, Taiwan (Invited speaker)
4. Experimental Models for Aging and Sarcopenia. 10th international conference on cachexia,sarcopenia & muscle wasting, Roma, Italy (Invited speaker)
5. Functional Foods for Muscle Atrophy in Aging and Diseases. 10th International Conference and Exhibition on Nutraceuticals & Functional Foods (ISNFF 2017), Gunsan, Kroea (Invited speaker)
6. Oligonol attenuates muscle atrophy in diabetes. International Congress on Nutrition and Integrative Medicine (ICNIM 2017), Sapporo, Japan (Invited speaker)
7. Bioactive natural products and genes involved in glucose/lipid homeostasis. Asia-Pacific Nutrigenomics & Nutrigenetics Organisation (APNNO), GyeongjuSouth Korea (Invited speaker)
8. The biological activities of Oligonol in diabetes and diet-induced insulin resistance. International Congress on Nutrition and Integrative Medicine (ICNIM2016), Sapporo, Japan (Invited speaker)
9. Oligonol protects against palmitate-induced senescence and insulin resistance in C2C12 muscle cells and promotes survival and prevents muscle atrophy in obese diabetic (db/db) mice. International Congress on Nutrition and Integrative Medicine (ICNIM 2015), Sapporo, Japan (Invited speaker)
10. Nutrition and health promotion- From Molecular to Physiological Modulation. ACN 2015 12th Asian Congress of Nutrition, Yokohama, Japan (Invited speaker)

全部論文著作連結

專利

技術轉移